Antibody characterization from COVID-19 patient plasma binding to SARS-COV-2 antigens

In this technical note, we show how the Creoptix WAVE can be used for the characterization of binding affinity and kinetics of antibodies raised against SARS-CoV-2 in clinical human blood plasma samples. With innovative disposable, no-clog microfluidics and high sensitivity, the Creoptix WAVE opens the door for antibody characterization directly from clinical blood plasma samples. The methods described here are also compatible with high concentrations of serum and plasma of SARS-CoV-2 patients’ samples. 

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