| 00:00:00 | Inhaler and nebulizer characterization |
| 00:01:17 | Inhaler and nebuliser characterisation |
| 00:01:47 | Inhaled drug deposition: important parameters |
| 00:03:37 | Spray characterisation: cascade impaction |
| 00:05:19 | Cascade impaction: advantages and disadvantages |
| 00:07:25 | Spray characterisation: why use laser diffraction? |
| 00:09:50 | How do laser diffraction systems measure particle size distributions? |
| 00:11:06 | How do laser diffraction systems measure particle size distributions? |
| 00:12:19 | Spraytec light scattering data |
| 00:13:35 | Comparing laser diffraction within cascade impaction |
| 00:17:09 | Laser diffraction: accessories for pharmaceutical spray measurements |
| 00:18:29 | What information does laser diffraction provide? |
| 00:20:25 | Dry Powder Inhalers: overview |
| 00:21:16 | A common view of dry powder dispersion… |
| 00:22:06 | The device and formulation must be considered together… |
| 00:23:16 | Hypothesis for dry powder delivery |
| 00:23:57 | Laser Diffraction study: experimental detail |
| 00:25:11 | Particle size flow rate dependence for the unprocessed lactose powder |
| 00:26:04 | Particle size flow rate dependence for the blended lactose / MgSt sample |
| 00:26:43 | Particle size flow rate dependence for the mechanofused lactose / MgSt sample |
| 00:27:25 | Concentration as a function of time for the blended lactose / MgSt sample |
| 00:28:18 | Concentration as a function of time for the mechanofused lactose / MgSt sample |
| 00:29:17 | Co-processing fine powders leads to changes in aerosolisation behaviour… |
| 00:30:24 | Co-processing fine powders leads to changes in aerosolisation behaviour… |
| 00:30:46 | Malvern Image Analysis Instrumentation |
| 00:32:09 | How does image analysis work? |
| 00:33:25 | Using shape to quantify agglomerates |
| 00:35:34 | Scattergram - Agglomerates |
| 00:37:13 | Scattergram – Primary Particles |
| 00:37:58 | Scattergram - Excipient Particles |
| 00:38:56 | Carrier free formulations |
| 00:40:19 | Effect of coating on circularity |
| 00:42:01 | Effect of coating on dispersion |
| 00:43:30 | Effect of coating on emitted dose |
| 00:45:33 | Nebulisers: overview |
| 00:47:11 | Gas-driven jet nebuliser performance |
| 00:48:22 | Breath-assisted nebuliser operation |
| 00:50:04 | Breath-assisted nebuliser operation: size histories for different breathing rates |
| 00:50:45 | Breath-assisted nebuliser operation: profiles for different formulation viscosities |
| 00:51:46 | Acknowledgements |
| 00:52:04 | Conclusions |
| 00:53:06 | Comparing laser diffraction within cascade impaction |
| 00:56:33 | Contact Information |
Here we describe the use of the Spraytec in optimizing the performance of pharmaceutical inhaler and nebuliser systems.