Method transfer – from the Zetasizer Nano to the Zetasizer Advance series

In this webinar, Dr. Nelli Laleni introduces the Zetasizer Advance range — the latest generation of light scattering instruments for measuring particle size, zeta potential, and molecular weight using DLS, ELS, and SLS. 

Building on the trusted foundation of the Zetasizer Nano, we’ll highlight the key differences between the two ranges, guide you in choosing the best Advance model for your applications, and show how to seamlessly transfer methods from Nano to Advance.

Login or register and watch the webinar today to learn how to future-proof your workflows with Zetasizer Advance.


Key moments

  • 00:10 – Introduction: Overview of Nano and Advance product families
  • 02:30 – Nano history: Models, strengths, and legacy features
  • 06:40 – Advance innovations: Adaptive correlation, multiple angle detection, fluorescence/polarization filters
  • 12:20 – Cell compatibility: Which Nano cells still apply, and what’s new
  • 16:50 – Measurement process: Dust rejection vs. adaptive correlation explained
  • 21:30 – Zeta potential: How constant current mode improves high-conductivity measurements
  • 26:45 – Model equivalence: How to choose the right Advance replacement for your Nano
  • 30:30 – Q&A highlights: Audience questions on concentration, sample types, and measurement limits

Key Takeaways

  • Continuity without compromise: Most Nano methods can be directly transferred, with only minimal adjustments for concentration or settings.
  • Improved sensitivity: Redesigned optics and low-volume sizing cells extend measurement ranges and reduce artifacts.
  • Faster, smarter workflows: Adaptive correlation accelerates measurements while improving robustness.
  • Greater reliability: Constant current mode ensures stable zeta potential results, even in challenging buffers.
  • Clear upgrade paths: Simple equivalence mapping helps identify the best Advance model for your Nano replacement.

What do our customers say?

"The Zetasizer Nano was a game changer for DLS when it launched — but the Advance brings improvements that make method transfer not just possible, but seamless."

"Adaptive correlation means no data is thrown away. You see both steady-state results and outlier events, giving you a richer picture of your sample."

"For high-conductivity samples, constant current mode maintains repeatability where the Nano would drift."


Recommended resources


演讲嘉宾

  • Dr. Nelli Laleni - Applications Specialist, Malvern Panalytical

    Dr. Nelli Laleni earned her Ph.D. in Chemical Engineering from the University of Birmingham, where she worked within the Food Microstructure Group under the supervision of Dr. Fotis Spyropoulos. Her doctoral research explored the multifunctional role of propolis particles in aqueous dispersions and oil-in-water emulsions.

    Nelli later joined Malvern Panalytical as an Applications Specialist in nanomaterial characterization. In her role, she delivers applications expertise and technical support across the customer journey — from proof-of-principle studies and instrument demonstrations to training and ongoing post-sales support.

    Keep up to date with Dr. Laleni: LinkedIn


更多信息

Who should attend? 

  • Scientists and researchers interested in upgrading their Zetasizer Nano to the Advance
  • Anyone interested in the new capabilities of the Zetasizer Advance series

What will you learn? 

  • Learn the differences in terms of hardware and which model would be the most appropriate for a direct replacement
  • Discover differences and similarities in terms of method development and available cells
  • Understand why there might be a few differences when it comes to size results