| 00:00:00 | Molecular Characterization of Therapeutic Polymers and Biomaterials |
| 00:01:24 | Untitled |
| 00:02:01 | Webinar Outline |
| 00:02:59 | Therapeutic Polymers and Nanomedicine |
| 00:05:28 | What are Therapeutic Polymers? |
| 00:06:54 | Common Polymers Used As Therapeutics |
| 00:07:56 | Accurate Molecular Characterization |
| 00:09:14 | SEC - The Separation Process |
| 00:10:42 | Triple or Tetra Detection SEC |
| 00:13:51 | Advanced SEC Configuration |
| 00:14:57 | Untitled |
| 00:16:21 | Application Examples |
| 00:18:09 | Glatiramer Acetate - Copaxone |
| 00:19:11 | Glatiramer Acetate Analysis Outline |
| 00:20:05 | Tetra Detection SEC Analysis |
| 00:23:03 | Photo-diode Array UV Data |
| 00:24:30 | Aggregation and Stability |
| 00:26:03 | Pentosan Polysulfate (PPS) - Elmiron |
| 00:27:06 | PPS Analysis Outline |
| 00:27:49 | Triple Detector Chromatograms |
| 00:29:59 | Structural Differences – MHS Plot |
| 00:31:31 | Polymeric Excipients |
| 00:32:26 | Accurate, High-throughput Characterization |
| 00:34:10 | Pre-formulation Analysis of PVP |
| 00:35:13 | Triple Detection SEC Analysis |
| 00:36:52 | Structural Differences – MHS Plot |
| 00:38:15 | Post-formulation Analysis of HEC |
| 00:39:26 | Triple Detector Chromatograms |
| 00:41:43 | Structural Differences – MHS Plot |
| 00:42:58 | Protein-PEG Conjugate Outline |
| 00:44:11 | Tetra-detection SEC |
| 00:46:23 | Tracking Aggregation |
| 00:47:14 | Conclusions |
| 00:49:55 | Tetra Detection SEC Analysis |
| 00:51:03 | Triple or Tetra Detection SEC |
| 00:52:35 | Triple Detector Chromatograms |
| 00:55:19 | Triple or Tetra Detection SEC |
| 00:56:42 | Structural Differences – MHS Plot |
| 01:00:08 | Contact Information |
Synthetic polymers and peptides can offer advantages over small molecule drugs and can be tailored to impart critical binding, solubility, and biocompatibility properties. SEC has an important role in the characterization of these materials