00:00:00 | Welcome |
00:02:59 | Forensic Analyses by Morphologically Directed Raman Spectroscopy |
00:03:20 | Overview |
00:03:53 | Introduction |
00:03:54 | Morphology in Forensic Science |
00:04:46 | Raman Spectroscopy in Forensic Science |
00:05:35 | Morphology + Raman Spectroscopy in Forensic Science |
00:06:18 | What is the MDRS? |
00:07:25 | Chemical correlation |
00:09:02 | Basic principles of MDRS |
00:09:57 | Forensic Application #1MDRS of Hoax Powders |
00:10:15 | The Hoax Powder Problem |
00:10:48 | Example |
00:11:30 | Materials and Methods – Artificial Sweeteners: Part A |
00:11:50 | Analytical Conditions |
00:12:28 | Methods |
00:12:50 | Results - Overall particle size distribution of blends |
00:13:15 | Results - PSD of MDRS Identified Bulking Agent |
00:13:34 | Results - PSD of MDRS Identified Sweetener |
00:14:21 | Results: Percentage Volume Distributions |
00:14:50 | Materials and Methods – Artificial Sweeteners: Part B |
00:15:21 | Name Brand vs. GenericNutritive Dextrose |
00:15:32 | Name Brand vs. GenericSucralose |
00:15:59 | Materials and Methods-White Powders |
00:16:39 | Results: Overall Distribution of Blend |
00:17:06 | Results: Flour & Baking Soda Distributions |
00:17:24 | Advantages of MDRS |
00:17:38 | Results: Chalk & Table Sugar Distributions |
00:18:01 | Volume Contributions vs Particle Size Contributions |
00:18:43 | ConclusionsHoax Powders |
00:19:12 | Forensic Application #2 |
00:19:18 | The Illicit & Counterfeit Drug Problem |
00:20:31 | Illicit Drug Mixture |
00:20:57 | PSD of 2 Components in the Illicit Drug Mixture |
00:21:40 | Illicit Drug Mixture- Morphology |
00:22:15 | Illicit Drug Mixture – Particle Size Distributions & Morphologies |
00:22:44 | Bath Salts |
00:23:30 | MDRS of Bath Salts |
00:23:46 | Bath Salts – “Arctic Rush” |
00:24:18 | Bath Salts – “Arctic Rush”L-Dopa & Caffeine |
00:24:56 | Bath Salts – “Fast Forward” |
00:25:35 | Over-the-counter drugs |
00:26:47 | Contaminated Drugs |
00:28:21 | Counterfeit Drug Problem |
00:28:59 | Counterfeit Drug Problem |
00:29:40 | Counterfeit Viagra |
00:30:05 | Counterfeit Viagra |
00:30:29 | Counterfeit Viagra |
00:30:58 | ConclusionsIllicit & Counterfeit Drugs |
00:31:35 | Forensic Application #3 |
00:31:40 | Why Soil? |
00:32:30 | Soil (for Forensic Purposes) |
00:33:04 | Soil Complexity |
00:33:23 | Why MDRS for Soil Minerals? |
00:34:31 | Materials and Methods – Soil Minerals |
00:35:19 | Quartz Site B and C – Particle Morphologies |
00:35:45 | Quartz PSD –Sites B vs C |
00:36:26 | MDRS of Soil Minerals% Particle Count |
00:37:02 | Chemometrics: Principal Component Analysis |
00:38:46 | Chemometrics: Principal Component Analysis |
00:38:54 | PCA of Soil Mineral Data |
00:39:12 | ConclusionsSoil Minerals |
00:39:35 | Forensic Application #4 |
00:39:39 | Why GSR? |
00:40:51 | Nitrocellulose |
00:41:13 | Volume Distributions at Various Distances |
00:42:03 | ConclusionsGSR |
00:42:34 | Overall Conclusions |
00:43:07 | Acknowledgements |
00:43:28 | Thank You! |
00:48:10 | Contact Information |
Morphologically-Directed Raman Spectroscopy (MDRS) can be applied to a variety of forensic evidence types such as illicit drugs, counterfeit pharmaceuticals, hoax powders, soils and gunshot residues. It is a novel and reliable tool that enables criminalists to obtain more information from forensic samples than is currently employed for investigations and adjudications.
MDRS combines automated particle imaging and Raman spectroscopy in one instrument. Particle imaging is performed to determine particle size and shape distributions of components in a blended sample. Particle size is an important physical property of particulate samples because it has a direct influence on a variety of material properties such as reactivity or dissolution rate, suspension stability, efficacy of delivery, texture, feel, appearance, flowability, handling, viscosity, packing density and porosity. Although measurement of particle size distributions is routinely carried out across a wide range of industries and is often a critical parameter in the manufacture and analysis of many products and substances, it is not widely used in the forensic sciences.
Raman spectroscopy is a useful technique in forensic science for determining molecular chemistry because it is rapid, reliable, does not require contact with the sample, and is non-destructive. Combining these two analytical techniques allows the individual components present within a blend or mixture to be independently characterized and compared. This presentation will demonstrate how such a tool can be used to gain a better understanding of mixtures across many areas of forensic science, as it is applicable to a range of Raman-active samples.