We offer brain slice assays as a low-throughput validation model of your test compound in a complex, multicellular approach. Slice cultures contain and maintain all the relevant neuronal and glial cells, structure and organization of the brain in thick sections of cultured ex vivo tissue providing a powerful translational link between in vitro and in vivo CNS studies in important therapeutic areas such as MS, Parkinson’s and Alzheimer’s disease.
We tailor the assay readouts to suit you. These can include immunohistochemical-based analysis or gene expression studies using qPCR or NGS techniques.
Contact us today to discuss how we can support your CNS research program.